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Showing posts from September, 2026

Epitranscriptomics in Cancer: How RNA Modifications Are Shaping Precision Oncology

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  Epitranscriptomics in Cancer: How RNA Modifications Are Shaping Precision Oncology Introduction Cancer biology is increasingly understood as a complex network of genetic, epigenetic, transcriptional, and post-transcriptional processes. While genomics has transformed the understanding of mutations and alterations that drive cancer, researchers are now focusing on another important layer of biological regulation: the chemical modification of RNA molecules . This emerging field is known as epitranscriptomics . RNA was traditionally viewed primarily as an intermediate molecule that carries genetic information from DNA to proteins. Modern RNA biology has demonstrated that RNA molecules are extensively modified after transcription and that these modifications can influence RNA stability, processing, localization, translation, degradation, and interactions with regulatory proteins. More than 170 RNA modifications have been identified across different RNA species, creating a comp...

Digital Biomarkers in Oncology: How Wearables and Patient-Generated Data Are Transforming Cancer Care

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  Digital Biomarkers in Oncology: How Wearables Are Transforming Cancer Care Introduction Cancer care is increasingly moving beyond traditional clinical measurements toward continuous, data-driven approaches that can provide a more detailed picture of how patients respond to disease and treatment. One of the emerging technologies contributing to this transformation is the use of digital biomarkers . Digital biomarkers are measurable, quantifiable physiological, behavioral, or functional characteristics that can be collected through digital technologies such as smartwatches, fitness trackers, wearable sensors, smartphones, connected medical devices, and remote monitoring platforms. In oncology, these technologies are being investigated for their potential to capture information about physical activity, sleep, heart rate, mobility, physiological changes, treatment tolerance, symptoms, and other aspects of a patient's daily life. The concept is particularly important becau...