International Experts Summit on Oncology & Cancer Care (Oncology Summit-2027)

  Functional Precision Oncology: Testing Cancer Cells to Find the Right Treatment Cancer treatment is becoming increasingly personalized. Instead of relying only on the cancer's location or a broad diagnosis, researchers and clinicians are looking for ways to understand the unique biological characteristics of each patient's tumor. Genomic sequencing, biomarkers, liquid biopsy, immunotherapy, and other precision oncology approaches have already changed how cancer is studied and treated. However, one important question remains: Can we directly test a patient's cancer cells to determine which treatment is most likely to work? This is where functional precision oncology is gaining attention. Functional precision oncology focuses on observing how a patient's actual cancer cells respond to different therapies. Rather than relying exclusively on genomic information to predict treatment response, researchers can use patient-derived tumor cells or related experimenta...

  Cancer Dormancy: How Hidden Tumor Cells Survive, Reactivate and Drive Cancer Recurrence Introduction Cancer treatment has advanced dramatically over the past several decades, with improvements in surgery, radiation therapy, chemotherapy, targeted therapies, immunotherapy, and precision oncology helping many patients achieve remission. However, one of the most challenging problems in cancer care remains recurrence . A tumor may disappear clinically after treatment, yet cancer can sometimes return months or even years later. One important biological explanation for this phenomenon is cancer dormancy . Cancer dormancy refers to a state in which cancer cells remain alive but temporarily stop, or greatly reduce, their proliferation. These cells may survive in tissues or distant organs without producing detectable disease. Although dormant cancer cells may remain clinically silent for extended periods, changes in their cellular environment, immune surveillance, signaling pathways, or s...

  Cancer-Associated Fibroblasts (CAFs): Understanding Their Role in Tumor Progression, Metastasis and Therapy Resistance Introduction Cancer is not driven by malignant cells alone. Within every tumor exists a complex ecosystem made up of immune cells, endothelial cells, extracellular matrix components, blood vessels, signaling molecules, and stromal cells that interact continuously with cancer cells. Among these stromal components, cancer-associated fibroblasts (CAFs) have emerged as important regulators of tumor development, progression, metastasis, and therapeutic response. Fibroblasts are connective-tissue cells that normally contribute to tissue structure, wound healing, extracellular matrix organization, and tissue repair. However, in the tumor microenvironment, certain fibroblasts can become activated and acquire distinct functional properties. These activated stromal cells are commonly referred to as cancer-associated fibroblasts. CAFs are increasingly recognized as...